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Research Publications of Prof. Rajiv K. Saxena

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Complete list of Research Publications of Prof. RK Saxena

1974 to 2023
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  1. Saxena, R.K. and Talwar, G.P. (1974).   A new in vitro method for  assay  of biological activity of growth hormone.  Acta.  Endocrinol. 76, 248-259.
  2. Talwar, G.P., Pandian, M.R., Kumar, N., Hanjan, S.N.S., Saxena, R.K., Krishnaraj, R. and Gupta, S.L. (1975). Mechanism of action of pituitary Growth Hormone.  Recent  Prog. Horm. Res. 31, 141-174.
  3. Talwar, G.P., Hanjan, S.N.S., Kidwai, Z., Gupta, P.D., Mehrotra, N.N., Saxena, R.K. and Bhattarai, Q.B. (1975). Growth hormone action on ExcerptaMedica International Congress Series No. 381, ExcerptaMedica, Amsterdam, pp.104-115.
  4. Talwar, G.P., Hanjan, S.N.S., Saxena, R.K., Pandian, M.R., Gupta, P.D. and Bhattarai, Q.B. (1975).  Regulation of Immune response by hormones In: Regulation of Growth and Differentiated Functions in Eukaryotic Cells (ed. G.P. Talwar). Raven Press, pp.271-281.
  5. Saxena, R.K. and Talwar, G.P. (1977). An anterior pituitary factor stimulates thymidine incorporation in isolated thymocytes. Nature(London), 268, 57-58.
  6. Saxena, R.K., Saxena, Q.B. and Talwar, G.P. (1977).  A method for reducing salts in tissue extracts containing low molecular weight compounds.  Indian J. Biochem. Biophys. 14, 299-301.
  7. Saxena, R.K., Jailkhani, B.L. and D’Monte, B. (1977).  Metabolic effects of steroid hormones, a feasible practical exercise for undergraduate medical students.  J. All India Institute of Medical Sciences, 3, 59-61.
  8. Saxena, R.K. and Saxena, Q.B. (1978).  Studies on a pituitary factor which stimulates DNA synthesis in isolated thymocytes.  Part I.Properties, specificity of action and chemical nature.  Indian J. Biochem. Biophys. 15, 427-432.
  9. Saxena, R.K. (1978).   Studies on a pituitary factor which stimulates DNA synthesis in isolated thymocytes. Part II.Partial purification and characterization. Indian J. Biochem. Biophys. 15, 433-438.
  10. Saxena, Q.B. and Saxena, R.K. (1978).  Studies on a pituitary factor which stimulates DNA synthesis in isolated thymocytes.  Part III. Effect on cultured thymocytes and embryonic thymus lobes maintained in organ culture.  Indian J. Biochem. Biophys. 15, 439-442.
  11. Saxena, Q.B. and Saxena, R.K. (1979).Studies on a pituitary factor which stimulates DNA synthesis in isolated thymocytes.  Part IV.Effect on cell size of thymocytes.  Indian J. Biochem. Biophys. 16, 204-208.
  12. Saxena, Q.B. and Saxena, R.K. (1979).Studies on a pituitary factor which stimulates DNA synthesis in isolated thymocytes.  Part V.  Locus  of  action.  Indian J. Biochem. Biophys. 16, 209-211.
  13. Saxena, R.K. and Saxena, Q.B. (1979).Studies on a pituitary factor which stimulates DNA synthesis in isolated thymocytes.  Part VI.  In vivo action.  Indian J. Biochem. Biophys. 16, 212-215.
  14. Saxena, R.K. and Adler, W.H. (1979).Modulation of natural cytotoxicity by alloantibodies. I. Alloantiserum enhancement of cytotoxicity of mouse spleen cells towards a human myeloid cell line.  J. Immunol. 123, 846-851.
  15. Saxena, R.K. (1980). The Thymus. In: Text Book of Biochemistry and Human Biology (ed. G.P. Talwar), Prentice Hall Publishers, pp.292-296.
  16. Saxena, R.K. (1980).  Growth Factors. In: Text Book of Biochemistry and Human Biology (ed. G.P. Talwar), Prentice Hall Publishers, pp.680-681.
  17. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1980). Modulation of natural cytotoxicity by alloantibodies. III. Augmentation of natural killer activity by allo-antisera directed against K, D and I regions of the murine H-2 complex.  Cellular Immunology, 59, 89-98.
  18. Saxena, R.K., Adler, W.H. and Nordin, A.L. (1980). Monoclonal anti thy-1 antibodies from hybridoma HO13-4 do not react with mouse natural killer cells.  Immunological Communications 9, 371-378.
  19. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1980).  Regulation of natural killer activity in vivo. I. Loss of natural killer activity during starvation.  Indian J. Expt. Biol. 18, 1383-1386.
  20. Saxena, R.K., Adler, W.H. and Nordin, A.A. (1981). Modulation of natural cytotoxicity by alloantibodies. IV. A comparative study of the activation of mouse spleen cell cytotoxicity by anti H-2 antisera, interferon and mitogens.  Cellular Immunology, 63, 28-41.
  21. Saxena, R.K., Spees, E.R. and Adler, W.H. (1981). Modulation of natural cytotoxicity by alloantibodies. II. Effect of anti HLA antisera on the natural activity of human peripheral blood lymphocytes against a human and murine cell line.  Indian J. Expt. Biol. 19, 595-597.
  22. Saxena, R.K. (1981). Studies on the mechanism of inhibition of natural killer cell mediated cytotoxicity by noncytotoxic (inert) lymphocytes. Indian J. Expt. Biol. 19, 812-818.
  23. Saxena, Q.B., Saxena, R.K. and Adler, W.H. (1981). Regulation of natural killer activity in vivo. IV. High natural killer activity in  alcohol drinking mice.  Indian J. Expt. Biol. 19, 1001-1006.
  24. Saxena, R.K., Saxena, Q.B. and Adler, W.R. (1981). Modulation of natural cytotoxicity by alloantibodies. V.  The mechanism of selective augmenting effect of anti H-2 antisera on the natural killer activity of mouse spleen cells.  Cellular Immunology, 65, 115-130.
  25. Saxena, Q.B., Saxena, R.K. and Adler W.H. (1982).  Regulation  of natural killer activity in vivo. III. Effect of hypophysectomy and growth hormone treatment on the natural killer activity of the mouse spleen cell population.  Int. Arch. Allergy and Applied Immunol. 67, 169-174.
  26. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1982).  Defective T-cell response in beige mutant mice.  Nature(London), 295, 240 – 241.
  27. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1982). Identity of effector cell participating in the reverse antibody dependent cell mediate cytotoxicity.  Immunology, 46, 459-464.
  28. Saxena, R.K. (1982).  Augmentation of mouse natural killer cell activity by alloantibody: A reverse ADCC reaction. In: NK cells and other natural effector cells (ed. R.B. Herberman), Academic Press, NY, pp.449-454.
  29. Saxena, Q.B., Saxena, R.K. and Adler, W.H. (1982).  Ethanol and natural killer activity.  In: NK cells and other natural effector cells (ed. R.B. Herberman), Academic Press, NY, pp.651-656.
  30. Saxena, R.K., Saxena, Q.B., Pyle, R.S. and Adler, W.H. (1982). Effect of anti-HLA and anti beta-2 microglobulin antisera on the natural cytotoxic activity of human NK cells and monocytes.  In: NK cells and other    natural effector cells (ed. R.B. Herberman), Academic Press, NY, pp.251-256.
  31. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1982).  Decline of murine natural killer activity  in response to  starvation,  hypophysectomy, tumor growth and beige mutation: A comparative study.  In: NK cells and other natural effector cells (ed. R.B. Herberman), Academic Press, NY, pp.645-650.
  32. Saxena, R.K. (1983).  Thymic Hormones.  In: Progress in Immunology of leprosy  (ed. G.P. Talwar, J.L. Turk and J.R.W. Rees),  Arnold-Heineman, New Delhi, pp.277-284.
  33. Saxena, R.K., Saxena, Q.B. and Collins, G.D. and Adler, W.H. (1983).  Augmentation of spleen natural killer activity in mice treated with interleukin-2 preparation.  Indian J. Expt. Biol. 21, 54-58.
  34. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1983/1984). Mechanism of loss of natural killer activity in P815 tumor bearing DBA/2 mice. Natural Immunity and Cell Growth Regulation, 3, 34-42.
  35. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1984).  Interleukin-2 induced activation of natural killer activity in spleen cells from old and young mice.  Immunology, 51, 719-726.
  36. Saxena, Q.B., Saxena, R.K. and Adler, W.H. (1984).  Effect of protein caloric malnutrition on the  level  of natural and inducible cytotoxic activities in mouse spleen cells.  Immunology, 51, 727-733.
  37. Saxena, Q.B., Saxena, R.K. and Adler, W.H. (1984).  Effect of feeding a diet with  half  of the recommended levels of all vitamins on the natural and inducible levels of cytotoxic activity in mouse spleen cells.  Immunology, 52, 41-47.
  38. Saxena, Q.B., Saxena, R.K. and Adler, W.H. (1986). Inhibition of human natural killer cell activity by ethanol.  Indian J. Exp. Biol. 24, 561-564.
  39. Saxena, R.K. (1987).  A spleen cell derived factor imparts resistance to NK cell mediated lysis in a mouse lymphoma cell line.  Immunology Letters, 15, 105-108.
  40. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1988).  Properties and characterization of a rat spleen cell derived factor which induces resistance to NK cell lysis in YAC lymphoma cells.  J. Immunol. 141, 1782-1787.
  41. Saxena, R.K., Saxena, Q.B. and Adler, W.H. (1988).  Lectin induced cytotoxic activity in spleen cells from old and young mice.  Immunology, 64, 457-461.
  42. Sarin, A. and Saxena, R.K. (1988).  Interleukin-2 induced activation of natural killer cells in rats and mice: A comparative study.  Asian Pacific J.Allergy, Immunology, 6, 88-94.
  43. Saxena, R.K., Chrest, J. and Adler, W.H. (1989).  Modulation of Major Histocompatibility Complex Antigens and inhibition of proliferative activity of YAC lymphoma cells by a Natural Killer Lysis Resistance Inducing Factor (NK-LRIF).  Natural Immunity and Cell Growth Regulation (USA) 8, 197-208.
  44. Sarin, A., Adler, W.H. and Saxena, R.K. (1989).  Lack of optimal activation of natural killer levels by interleukin-2 in rat spleen cells: Evidence for suppression.  Cellular Immunology 122, 548-554.
  45. Sarin, A. and Saxena, R.K. (1989).  Natural killer cells.  Indian J. Exp. Biol. 27, 583-592.
  46. Sarin, A. and Saxena, R.K. (1989).  Interleukin-2 induced changes in the buoyant density of cytotoxic cells and its relationship with proliferative activity.  Natural Immunity and Cell Growth Regulation, USA. 8, 279-289.
  47. Saxena, R.K. (1989).  NK-LRIF, a factor released by activated rat spleen cells, inhibits the susceptibility of certain tumor cells to lysis by NK cells.  In “Recent Trends in Biochemistry and Immunology”, G.N. Johri (ed). Published by Zoology Association, Vikram University. pp.63-68.
  48. Saxena, R.K. (1989).  Natural Killer Cells : Current Status.  In “Recent Trends in Biochemistry and Immunology”, G.N. Johri (ed). Published by Zoology Association, Vikram University. pp.69-72.
  49. Sarin, A. and Saxena, R.K. (1988).  Production by rat spleen cells of a suppressor of interleukin-2 induced activation of Natural Killer Cells.  In “Recent Trends in Biochemistry and Immunology”, G.N. Johri (ed.).  Published by Zoology Association, Vikram University. pp.47-53.
  50. Udaykumar, Sarin, A. and Saxena, R.K. (1989).  T- and B-cell reactivity of Mycobacterium tuberculosis antigens fractionated by iso-electric focusing.  In “Recent Trends in Biochemistry and Immunology”, G.N.. Johri (ed).  Published by Zoology Association, Vikram University.  pp.17-22.
  51. Saxena, R.K. (1990).  Modulation of MHC antigen expression and NK susceptibility of target cells by a rat spleen cell derived factor, in “Proceedings of the Indo-US Workshop on Cell Mediated Immunity in relation to Tropical Diseases” pp.111-120.
  52. Sarin, A. and Saxena, R.K. (1990).Quantitative estimation of major histo-compatibility complex antigens on live tumor cells.  Indian J. Expt. Biol. 28, 1017-1020.
  53. Saxena, R.K. (1990).  Cell mediated cytotoxicity responses in young and old mice.  In “Perspectives in Aging Research”, R. Singh, G.S. Singhal eds., pp.31-36.
  54. Sarin, A. and Saxena, R.K. (1990). Influence of ageing on the generation of adherent – lymphokine activated killer (A-LAK) cells in rat.  In: “Perspectives in Ageing Research”, R. Singh and G.S. Singhal eds., pp.37-43.
  55. Sarin, A. and Saxena, R.K. (1990).  Mechanism of a sub optimal NK activation by IL-2  in  the  rat  system.  In “Natural Killer Cells: Biology and Clinical Application”,   S. Karger Publishers, Basel, Switzerland. pp.186-189.
  56. Sarin, A. and Saxena, R.K. (1990).  Necessity for interaction between adherent and nonadherent rat spleen cells for the generation of a suppressor factor of NK activation.  Immunology letters 24, 93-96.
  57. Udaykumar, Sarin, R. and Saxena, R.K. (1991).  Analysis of circulating immune complexes (CIC) in tuberculosis: Levels of specific antibodies and antigens in CIC and relationship with serum antibody.  FEMS Microbiology Immunology, 76, 135-142.
  58. Udaykumar and Saxena, R.K. (1991). Antigenic epitopes on Mycobacterium tuberculosis recognized by antibodies in tuberculosis and mouse antisera.  FEMS Microbiology Immunology, 76, 7-12.
  59. Sarin, A. and Saxena, R.K. (1991). Restoration of Interleukin-2 induced NK activation by the depletion of adherent cells from rat spleen cells.  Med. Sci. Res. 19.
  60. Saxena, R.K. (1992).  Production and Bioassays of Interleukins.  In “A Handbook of Practical Immunology”, G.P. Talwar and S.K. Gupta (ed) , CBS Publishers , Delhi. pp282-288.
  61. Saxena, R.K., Saxena, Q.B., Sarin, A. and Herberman, R.B. (1992).  Natural Killer – Resistance  Inducing  Factor  (NK-RIF): a  new immunomodulatory cytokine.  In, “Natural Killer Cells: Receptors,        Signaling and Mechanisms”.  eds., E. Lotzova, and R.B. Herberman, CRC Press pp.381-392.
  62. Sarin, A. and Saxena, R.K. (1992).  Gamma interferon down regulates sensitivity of mouse tumor cell lines to lysis by adherent lymphokine activated killer cells.  Med. Sci. Res. 20, 183-184.
  63. Udaykumar and Saxena, R.K. (1992). Acid induced changes in the immune-reactivity of specific antigen and antibody in CIC from TB sera.  J. Clin. Lab. Analysis. 6, 194-200.
  64. Prabhu, A., Sarin, A. and Saxena, R.K. (1993).  Antigen specific suppressor influence of the carbohydrate determinants of the antigens derived from M. tuberculosis (M. tb) on T cell proliferative response.  Immunology and Infectious Diseases 3, 189-194.
  65. Sarin, A., Haridas, V. and Saxena, R.K. (1993).  MHC I class I up-regulation protects some but not all targets against LAK mediated lysis: possible implications for the existence of LAK cells subpopulations using different recognition strategies.  Immunology  letters 38, 59-62.
  66. Prabhu, A., Sarin, A. and Saxena, R.K. (1993).  B cell mitogenic activity of dinitrophenyl derivative of M. tuberculosis antigens. Cellular Immunology 149, 422-432.
  67. Sarin, A. and Saxena, R. K.. (1993).  Reversal of interferon induced LAK resistance in two murine cell lines by exposure to acid pH.  Current Science 65, 705-707.
  68. Udaykumar and Saxena, R.K. (1994).  E. coli reacting antibodies in human tuberculosis sera.  Indian J. Tuberculosis 41, 29-34.
  69. Prabhu, A., Udaykumar, Sarin, A. and Saxena, R.K. (1993). Immune response to environmental exposure or specific immunization with the antigens of Mycobacterium tuberculosis.  In: Environment and Physiology, B.N. Mallick and R. Singh (Eds.), Narosa Publishing House, New Delhi, pp 253-258.
  70. Haridas, V., Sarin, A., Kochupillai, V., Anandi, R. and Saxena, R.K. (1994).  Effect of gamma interferon on the expression of class I MHC antigens on fresh leukemia cells and their susceptibility to lysis by lymphokine activated killer cells. Indian J. Cancer 31, 96-102.
  71. Prabhu, A. and Saxena, R.K. (1994). Comparison of B-cell proliferative response to lipopolysaccharide and DNP derivative of tuberculosis  antigens.  J. Biosciences 19, 57-65.
  72. Haridas, V. and Saxena, R.K. (1995).  Changes in LAK susceptibility of tumor cells as their MHC I antigen expression levels regenerate after pH 3.0 treatment. Immunology  Letters  44, 7-11.
  73. Haridas, V. and Saxena, R.K. (1995).  Role of MHC I antigens  in modulating the performance  of  murine  tumor cells in cold target competition assays. Immunology 84, 86-90.
  74. Haridas, V. and Saxena, R. K. (1995). Interferon modulation of levels of class I MHC antigens on some tumor cell lines and its correlation with          inhibition assays. Cellular Immunology 161, 256-261.
  75. Sarin, A., Saxena, Q.B.,  Herberman, R.B. and  Saxena, R.K. (1995).  Enhanced MHC I antigen  expression on tumor target cells is inversely correlated to lysis by allogeneic but not by xenogeneic NK cells.  J. Biosciences 20, 515-523.
  76. Saxena, R.K., Haridas, V. and Sarin, A. (1995). Regulation of NK susceptibility  by  target  cell  class  I MHC molecules. Indian J. Biochemistry and  Biophysics  32, 179-185.
  77. Saxena, R.K., Collins, G. D., Chrest, F.J. and Adler, W.H. (1996). Bcl-2 transfaction protects Hut78 cell line from different types of cytotoxic effector cells.  Immunology Letters 52, 95-98.
  78. Saxena, R. K. (1996). Understanding inverse  correlation between  the levels of class I major histocompatibility  complex antigens on tumor cells and their susceptibility to Natural Killer cells: Evidence of competition experiments.  Current Science, 70, 143-146.
  79. Saxena, R.K. (1996).  Research Funding in India.  Some thoughts, some pipe dreams.  Bulletin of the Indian Immunology Society,  Sept. 1996 issue.
  80. Saxena, R.K., Saxena, Q.B., Whiteside, T.L., Goldfarb, R.B. and Herberman, R.B. (1996). Partial purification and characterization of a novel human factor that augments the expression of class I MHC antigens on tumor cells.  J. Biosciences,  21, 13-25.
  81. Saxena, Q.B., Saxena, R.K., Goldfarb, R.B., Herberman, R.B. and Whiteside, T.L. (1996). Identification and partial purification of a human Natural Killer cell proliferation-inducing factor.  Biosciences , 21, 455-469.
  82. Raval, A., Puri, N. and Saxena, R. K. (1997). Generation of human class I MHC antigen activating factor (MHC-AF) in serum free medium and its partial purification. J. Biosciences 22,  59 – 68.
  83. Saxena, R. K. (1997).  Missing self by heterogeneous NK cells. J. Biosciences 22, 3 – 12.
  84. Haridas, V. and Saxena, R. K. (1997). Mechanism of interaction of pH 3.0 treated tumor cells expressing lower levels of class I MHC antigens, with    IL-2 activated NK cells .  Immunology Letters  55, 167-171
  85. Saxena, R. K. (1997) Ontogeny of inhibitory receptors for MHC molecules on NK cells.  Immunology Today 18, 146
  86. Puri, N., Raval, A. And Saxena, R. K. (1997) Species specificity of an actvated spleen cell derived factor which augments the expression MHC class I antigens on tumor cells. Expt. Mol. Med. 29, 129-132.
  87. Saxena, R.K. (1997).  Preface on research and teaching in Immunology in India,  for Immunology Special issue.  Biosciences,  Jan. 1997 issue.
  88. Saxena, R.K. (1997). Biomedical Research Funding in India: Time to wake up. (Editorial)  National Medical Journal of India,  10, 105-106.
  89. Saxena, R. K. (1997). Funding Higher Education: Urgent need for alternatives. JNU News, 15, 16-17. 
  90. Saxena, R. K., Malik,, Udaykumar,  R., Chandrashekhar,  B., Myneedu, V. P. ,  Jain, N. K.  and  Jain,  R. C.  (1998)  Detection of M. Tuberculosis antigens in body fluids of tuberculosis patients,  in “Microbes for Health, Wealth and Sustainable Environment”,  A. Verma (ed), Malhotra Publishing House, New  Delhi. pp 659-668.
  91. Dhillon, S. and Saxena, R.K. (1998)  Tumor specific boosting of IL-2 induced NK activation by paraformaldehyde fixed tumor cells. Immunol. Letters 63, 153-158.
  92. Raval, A., Puri, N., Rath, P. C. and Saxena, R. K. (1998)  Cytokine regulation of expression of class I MHC antigens. Exp. Mol. Med. 30, 1-13.
  93. Puri, N. and Saxena, R. K. (1998) Induction of proliferation in resting B             cell by a factor released by activated mouse spleen cells. Exp. Mol. Med. 30, 199-204.
  94. Puri, N. and Saxena, R. K. (1998) Partial purification and characterization of a murine factor which augments the expression of MHC I molecules on tumor cells. Exp. Mol. Med.  30, 93-99. 
  95. Saxena, R. K. and Siddiqui, S.M. (1998)CpG containing oligo-deoxynucleotides as new generation adjuvants in DNA and protein vaccines. (Comments) Biosciences 23, 164-165. 
  96. Saxena, R.K. and Dhillon, S. (1998) Influence of tumor cells on NK cell system.  Proceedings of the  Tenth International Congress of Immunology.  GP Talwar, I Nath, NK Ganguly and KVS Rao edited, MonduzziEditore, Italy, 237-242.
  97. Saxena, R.K. (1998) Continuing Education in Immunology. Immunol. Today. 19, 437.
  98. Dhillon, S., Das, A. and Saxena, R.K. (1999)  Activating and inhibitory receptors on Natural Killer cells.  Nat. Acad. Sci. (India)  69 (B), III&IV, 229-243
  99. Dhillon, S. and Saxena, R.K. (1999) Upregulation of KIR expression on murine bone marrow cells by IL2 and paraformaldehyde fixed tumor  Immunology Letters 170, 157 – 163.
  100. Saxena, K. and Adler, W.H.  (1999). Cytolytic activity of mitogen activated old and young mouse spleen cells against tumor target cells expressing high or low levels of Fas antigen. Expt. Mol.  Medicine 31, 137-141
  101. Chander, A., Yadava, R., Ghosh, S., Rath, P.C., Yadava, P.K., Orm, I.M. and Saxena, R. K. (2000)Strain Differentiation Among Indian Clinical Isolates of tuberculosis by RFLP Analysis. Molecular Biology Today 1(2): 53-55.
  102. Saxena, R.K. and Chandrasekhar, B. (2000) A novel non-phagocytic mechanism of erythrocyte destruction involving direct cell mediated lysis. International J. Hematology  71, 227-237.
  103. Siddiqui, S.M., Orme, I.M. and Saxena, R.K. (2000) Efficacy of culture filtrate protein preparations from some Indian isolates of M. tuberculosis to activate T cells derived from healthy donors. Int. J. Tuberculosis and Lung Diseases 4 (10), 980-987.
  104. Saxena, R.K. (2000) Should erythrocyte destruction in vivo be through phagocytosis alone? J. Biosciences 25, 3-5.
  105. Saxena, R.K. (2001) Natural killer cells in immunotherapy. CDRI journal (in press)
  106. Saxena, K. and Adler, W.H.  (2000). In Vitro erythrocidal activity of activated spleen cells from young and old mice. Expt. Gerontology 35, 409-416.
  107. Das, A. and Saxena, R.K. (2001)Abrogation of tumor induced KIR expression on mouse spleen cells by Mitomycin C.  Immunology Letters 77, 73-77.
  108. Das, , Sarin, A. and Saxena, R.K. (2002)Modulation of NK cell activation and interaction with target cells. Proc. Indian Natl. Acad. Sci. (PINSA) B68, 1, 47-60. 
  109. Choudhry, V. and Saxena, R.K. (2002) Detection of tuberculosis antigens in urinary proteins of tuberculosis patients. European Journal of Clinical Microbiology and Infectious Diseases. 21, 1-5.
  110. Saxena, R.K., Wiessman, D., Simpson, J. and Lewis, D.M. (2002) Murine model of BCG lung infection: Dynamics of lymphocyte subpopulations in lung interstitium and tracheal lymph nodes. J. Biosciences 27, 143-153 
  111. Saxena, R.K., Wiessman, D., Saxena, Q.B., Simpson, J. and Lewis, D.M. (2002) Kinetics of changes in lymphocyte sub-populations in mouse lungs after intrapulmonary infection with M. bovis (Bacillus Calmette-Guerin) and identity of cells responsible for IFNγ responses Clin. Exp. Immunol 128, 405-410 
  112. Saxena, R.K., Valliyathan, V. and Lewis, D.M. (2003) Evidence for LPS-induced differentiation of RAW264.7 murine macrophage into dendritic like cells. J. Biosciences 28, 129-134
  113. Saxena, R.K., Saxena, Q.B., Weissman, D.M., Simpson, J., Bledsoe, T.A. and Lewis, D.M. (2003) Effect of diesel exhaust particulate (DEP) on Bacillus Calmette-Guerin (BCG) lung infection in mice and the attendant changes in lung interstitial lymphoid subpopulations and IFN gamma response. Toxicological Sciences 73, 66-71.
  114. Saxena, Q.B., Saxena, R.K., Siegel, P.D. and Lewis, D.M. (2003) Identification of organic fractions of diesel exhaust particulate (DEP) which inhibit nitric oxide (NO) production from a murine macrophage cell line Toxicology Letters 143, 317-22.
  115. Das, A., Dhillon, S. and Saxena, R.K. (2003)Modulation of NK cell activation by tumor cells: Role of receptors for MHC I molecules. In “Progress in Hematologic Oncology”,  (ed. Lalit Kumar) The Advanced Research Foundation, New York. pp 191-198. 
  116. Siegel, P.D., Saxena, R.K., Saxena, Q.B., Ma, J.K.H., Ma, J.Y.C., Yin, X., Casternova, V, Al-Humadi, N. and Lewis, D.M. (2004) Effect of diesel exhaust particulate on immune response: Contribution of particulate vs. organic soluble components. J. Toxicol. Environ. Health. (A) 67, 221-31.
  117. Saxena, R. K., Choudhry, V., Nath, I., Das, S.N., Paranjape, R.S., Babu, G., Ramlingam, S., Mohanty, D., Vohra, H., Thomas, M., Saxena, Q.B. and Ganguly, N.K. (2004) Normal ranges of some select lymphocyte subpopulations in peripheral blood of normal healthy Indians: Results of a task force study. Current Sciences 86, 969-975
  118. Das, A., Gupta, M. K. and Saxena, R.K. (2004) Enhanced activation of murine NK cells by IL2 in presence of circulating immune complexes. Current Science 87, 780 – 783
  119. Das, A. and Saxena, R.K. (2004) Role of interaction between Ly49 inhibitory receptors and cognate MHC I molecules in IL2 induced development of NK cells in murine bone marrow cell cultures. Immunology Letters 94, 209-214
  120. Ghosh, S. and Saxena, R.K. (2004) Early effect of Mycobacterium tuberculosis infection on Mac-1 and ICAM-1 expression on mouse peritoneal macrophages, Experimental Molecular Medicine 36, 387-395
  121. Khandelwal, S. and Saxena, R.K. (2006) Assessment of survival of aging erythrocyte in circulation and attendant changes in size and CD147 expression by a novel two step biotinylation method. Experimental Gerontology 41 :855-61
  122. Khandelwal, S. and Saxena, R.K. (2007) Reduced expression of CD47 during murine erythrocyte senescence and its role in erythrocyte clearance from circulation. Transfusion 47(9): 1725-32.
  123. Saxena, R.K., Williams, W. and Gilmour, M.I. (2007) Suppression of basal and cytokine induced expression of MHC, ICAM 1 and B7 markers on mouse lung epithelial cells exposed to diesel exhaust particles. Am. J. Biochem. Biotechnol. 3 (4) : 187-192
  124. Gilmour, M.I., Stevens, T., Saxena, R.K. (2007) Effect of Particles on the Immune System, in ‘Particle Toxicology’ (Ed. K. Donaldson & P. Borm) CRC Press, NY, (pp245-258)
  125. Khandelwal, S. and Saxena, R.K. (2007) Age dependent increase in green auto-fluorescence of blood erythrocytes J. Biosciences 32 (6), 1139 – 1145.
  126. Saxena, R.K., Williams, W., McGee, J.K., Daniels, M.J., Boykin, E. and Gilmour, M.I. (2007) Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-wall carbon Nanotubes. Nanotoxicology 1: 291-300
  127. Saxena, R.K., Gilmour, M.I. and Hays, M.D. (2008) Isolation and quantitative estimation of diesel exhaust and carbon black particles ingested by lung epithelial cells and alveolar macrophages in vitro. BioTechniques 44, 799-805.
  128. Khandelwal, S. and Saxena, R.K. (2008) A role of phosphatidylserine externalization in clearance of young erythrocytes exposed to stress but not in eliminating aging populations of erythrocyte. Experimental Gerontology 43, 764-70Article selected by Faculty of 1000, with a rating of 10 (Exceptional) [f1000.com]
  129. Lalitha, P.V., Biswas, S., Pillai, C.R. and Saxena, R.K. (2008) Immunogenicity of a recombinant malaria vaccine candidate, domain I+II of AMA-1 ectodomain, from Indian P. falciparum alleles. Vaccine 26, 4526-35
  130. Salam, N., Gupta, S, Sharma, S., Pahujani, S., Sinha, A., Saxena, R.K., Natarajan, K. (2008) Protective immunity to Mycobacterium tuberculosis infection by chemokine and cytokine conditioned CFP-10 differentiated dendritic cells. PLoS ONE 3(8):e2869
  131. Gupta, S, Salam, N.,  Srivastava, V., 1, Singla, R.,  Behera, D., Khayyam, K.U., Korde, R.,  Malhotra, P., Saxena, R., Natarajan, K.(2009). Voltage Gated Calcium Channels Negatively Regulate Protective Immunity to Mycobacterium tuberculosis. PLoS ONE  4(4),  e5305
  132. Saxena, R.K. and Khandelwal, S. (2009) Aging and destruction of erythrocytes in mice. Current Science 97, 500-507.
  133. Saxena, R.K., Gilmour, M.I., Schladweiler, M.C., McClure, M., Hays, M. and Kodavanti, U.P. (2009). Differential Pulmonary Retention of Diesel Exhaust Particles in Wistar Kyoto and Spontaneously Hypertensive Rats. Toxicological Sci.111:392-401.
  134. Tong, H., McGee, J.K., Saxena, R.K., Kodavanti, U.P., Devlin, R. , Gilmour, M.I. (2009) Influence of Acid Functionalization on the Cardio-Pulmonary Toxicity of Carbon Nanotubes and Carbon Black Particles in Mice. Toxicology and Applied Pharmacology 239 :224-32. [This paper won a 2010 Scientific and Technological Achievement Awards from US Environmental Protection Agency] 
  135. Lalitha, P.V., Biswas, S., Pillai, C.R., Seth, R.K. and Saxena, R.K. (2010) Expression, purification and characterization of allelic variants of MSP-142 from Indian Plasmodium falciparum isolates. Vaccine 28: 4661-4667. 
  136. Saxena, R.K., McClure, M, Hays, M., Green, F.H.Y., McPhee, L.J., Vallyathan,           and Gilmour, M.I. (2010) Quantitative assessment of elemental carbon in the lungs of never smokers, cigarette smokers and coal miners. J. Toxicol. Environ. Health. 74: 706-715. 
  137. Kumari, M. and Saxena, R.K. (2011) Relative efficacy of uptake and presentation of BCG antigens by type I mouse lung epithelial cells and peritoneal macrophages. Infection and Immunity Infection and Immunity Aug;79(8):3159-67.
  138. Sachar, S and Saxena R.K. (2011) Cytotoxic effect of poly-dispersed single walled carbon nano-tubes on mouse erythrocytes. PLOS one 6(7):e22032.
  139. Kumari, M., Sachar, S. and Saxena, R.K. (2012) Loss of proliferative and antigen presentation activity following internalization of poly-dispersed single-walled carbon nanotubes by primary lung epithelial cells PLOS one 7 (2): e31890
  140. Saxena, R.K., Bhardwaj, N, Sachar, S, Puri, N. and Khandelwal, S (2012) A double in vivo biotinylation (DIB) technique for objective assessment of aging and clearance of mouse erythrocytes in blood circulation, Transfusion Medicine and Hemotherapy 39, 335-341
  141. Alam, A., Sachar, S., Puri, N. and Saxena, R.K. (2013). Interactions of poly-dispersed single walled Carbon Nanotubes with T cells resulting in down regulation of allogeneic CTL responses in vitro and in vivo. Nanotoxicology 7, 1351-1360 [Included as a Key Nanotechnology Articles on Global Medical Discovery web-portal (globalmedicaldiscovery.com]
  142. Bhardwaj N. and Saxena R. K. (2013) Heterogeneity of reticulocyte population in mouse peripheral blood. Current Science 105, 1611-1614.
  143. Bhardwaj N. and Saxena R. K. (2014) Elimination of young erythrocytes from blood circulation and altered erythropoietic patterns during paraquat induced anemic phase in mice. PLoS ONE 9(6): e99364
  144. Abbas, Z., Puri, N. and Saxena, R.K. (2014) Lipid antigen presentation through CD1d pathway in mouse lung epithelial cells, macrophages and dendritic cells and its suppression by poly-dispersed single-walled carbon nanotubes. Toxicology in vitro29, 1275 – 85
  145. Bhardwaj N. and Saxena R. K. (2015) Selective loss of younger erythrocytes from blood circulation and changes in erythropoietic patterns in bone marrow and spleen in mouse anemia induced by poly-dispersed single wall carbon nanotubes. Nanotoxicology9(8):1032-40.
  146. Chatterjee, S. and Saxena, R.K. (2015) Preferential elimination of older erythrocytes in circulation and depressed bone marrow erythropoietic activity contribute to cadmium induced anemia in mice.PLoS One10(7): e0132697. doi:10.1371/journal.pone.0132697
  147. Kumari, M. and Saxena, R.K. (2015) Proliferative activity and changes in the relative proportion of T1 and TII populations in cultured primary  epithelial cells, isolated from mouse lung. Cell Biology: Research and Therapy, 4, 3
  148. Alam, A., Puri, N. and Saxena, R.K. (2016)Uptake of poly-dispersed single-walled carbon nanotubes and decline of functions in mouse NK cells undergoing activation, Immunotoxicology, DOI: 10.1080/1547691X.2016.1191562
  149. Chatterjee, S., Bharadwaj, and Saxena, R.K. (2016) Identification of Stages of Erythroid Differentiation in Bone Marrow and Erythrocyte Subpopulations in Blood Circulation that Are Preferentially Lost in Autoimmune Hemolytic Anemia in MousePLoS One ;11(11): e0166878. https://doi.org/10.1371/journal.pone.0166878
  150. Chatterjee, S. and Saxena, R.K. (2017) A Double in vivo Biotinylation Technique to Assess Erythrocyte Turnover in Blood Circulation. In “Transfusion Medicine”, Ed. Dr. AnkieKoopman-van Gemert., InTech Publishers, European Union[ISBN: 978-953-51-5473-0] p 3-21 
  151. Alam, A. and Saxena, R.K. (2017)Natural Killer Cells Interaction with Carbon Nanoparticles. In “Natural Killer Cells”, Ed. MouradAribi,InTech Publishers, European Union http://dx.doi.org/10.5772/intechopen.69731ISBN: 978-953-51-5499-0, pp 140-160
  152. Chatterjee, S. and Saxena, R.K. (2017) Binding of Autoantibodies and Apoptotic Response in Erythroid Cells in the Mouse Model of Autoimmune Hemolytic Anemia. Hematology Transfusion International Journal, 5(2), 155
  153. Chatterjee, S. and Saxena, R.K. (2018)Erythrocyte Turnover and Erythropoietic Patterns in Two Different Experimental Mouse Models of Anemia. In “Frontiers in Clinical Drug Research – Hematology; Volume 3”, Ed. Atta-ur-Rehman, Bentham Science Publishers (ISBN Print: 978-1-68108-368-1), pp 220-240.
  154. Saxena, R.K. (2018) Modulation of the immune system by carbon nanoparticles, in Molecular Medicine: Bench to bedside (Festschrift in honor of Prof. GP Talwar), SK Gupta and NK Lohiya (Ed), Published by Indian Society for Study of Reproduction and Fertility, New Delhi (ISBN: 978-81-936756-0-1), pp 92-100
  155. Kumari, M, and Saxena, R.K. (2018)Evidence for an immunological role of mouse primary lung epithelial cells. Journal of Genetics and Cell Biology1, 3-6
  156. Babu Mia, Md. and Saxena, R.K. (2018) Phosphatidyl serine externalization in different age groups of mouse erythrocytes in response to agents that induceanemia. HematolTransfusInt J. 6(4):144‒149.
  157. Abbas, Z., Puri, N. and Saxena, R.K. (2018)Evidence of CD1d pathway of lipid antigen presentation in mouse primary lung epithelial cells and its up-regulation upon Mycobacterium bovis BCG infection. PLoS ONE 13(12): e0210116. https://doi.org/10.1371/journal.pone.0210116
  158. Dutt, T.S., Babu Mia, Md. and Saxena, R.K. (2019)Elevated internalization and cytotoxicity of poly-dispersed single-walled carbon nanotubes in activated B cells can be basis for preferential depletion of activated B cells in vivo. Nanotoxicology, 2019,DOI: 10.1080/17435390.2019.1593541)
  159. Dutt, T.S. and Saxena, R.K. (2019) Activation of T and B lymphocytes Induces Increased Uptake of Poly-Dispersed single-Walled Carbon Nanotubes and Enhanced Cytotoxicity. International Journal of Nanotechnology in Medicine & Engineering4:3, 16-25
  160. Dutt, T.S. and Saxena, R.K. (2019) Uptake of Carboxylated Fluorescent Nano-Diamonds by Resting and Activated T and B Lymphocytes and Comparison with Carbon Nanotube Uptake, International Journal of Nanotechnology in Medicine & Engineering 4:7, 61-68
  161. Singh, A. P., Md. Babu Mia and Saxena, R.K.(2020) Acid-functionalized single walled carbon nanotubes alter epithelial tight junctions and enhance para-cellular permeability. Biosciences45, 23
  162. Dutt, T.S. and Saxena, R.K. (2020) Enhanced antibody response to ovalbumin coupled to poly-dispersed acid functionalized single walled carbon nanotubes. Immunology Letters217, 77-83
  163. Behera, S.P and Saxena, R. K. (2020) Modulation of cell adhesion and migration by poly-dispersed-acid-functionalized-single-walled carbon-nanotubes in lung epithelial cellsBIORXIV-2020-056895v2
  164. Bhardwaj, D. and Saxena, R.K. (2020) Poly-dispersed-acid-functionalized-single-walled carbon nanotubes(AF-SWCNTs) are potent inhibitor of BCG induced inflammatory response in macrophage cell lines. BIORXIV/2020/056960
  165. Babu Mia, Md. And Saxena, R.K. (2020) In vitroand in vivo modulation of Hematopoietic Stem Cell (HSCs) differentiation into T and B cells by poly dispersed acid-functionalized single-walled carbon nanotubes (AF-SWCNTs) J Immunol,  May 1, 2020, 204 (Supplement) 62.131
  166. Babu Mia, Md. And Saxena, R.K. (2020) Poly dispersed acid-functionalized single walled carbon nano-tubes target activated T and B cells to suppress acute and chronic GVHD in mouse model. Immunology Letters 224, 30-37
  167. Behera, S.P. and Saxena, R.K. (2020)Suppression of in Vitro Wound Healing Process in Monolayers of Lung Epithelial Cells by Poly-dispersed-acid-functionalized-single-walled Carbon Nanotubes and Its Mechanism.International J. Nanotechnology in Medicine and Engineering,Volume 5 Issue 3, September 2020
  168. Bhardwaj, D. and Saxena, R.K. (2020) Uptake of diamond nanoparticles blocks inflammatory responses in macrophages. International J. Nanotechnology in Medicine and Engineering Volume 5 Issue 4, October 2020
  169. Bhardwaj, D. and Saxena, R.K. (2021) Poly-dispersed-acid-functionalized-single-walled carbon nanotubes (AF-SWCNTs) are potent inhibitor of BCG induced inflammatory response in macrophages. InflammationDOI 10.1007/s10753-020-01386-8
  170. Babu Mia, Md. And Saxena, R.K. (2021) Poly-dispersed single-walled carbon nanotubes induce cytotoxicity in bone marrow derived Hematopoietic Stem and Progenitor Cells and modulate their cytokine driven differentiation to immune cells. Current Res. Toxicology2, 82-92
  171. Behera, S.P. and Saxena, R.K. (2021)Nanodiamonds inhibit the scratch wound healing process in Lung Epithelial Cell Monolayers by inhibiting cell proliferation and migration.Toxicology Letters341, 83-93
  172. BabuMia Md, Pushpam D, Bakhshi S, Saxena RK (2022) Uptake of Poly-dispersed Carbon Nanotubes Induce Cytotoxic and Cytostatic Effect on Human B Cell Leukemia Cells. J ClinToxicol. 12:504.
  173. Behera, S.P, Tyagi, W, and Saxena, R.K. (2023) Carboxyl nanodiamonds inhibit melanoma tumor metastases by blocking cellular motility and invasiveness. PNAS Nexus, Volume 2, Issue 11, November 2023, pgad359-370

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